The end of the world will come, er..maybe not to non-believers of God...
As when God put the human race on the earth, He will someday take us off the earth for good.
According to Quran, doomsday (kiamat) will come when there is no more Azan (call for prayer) being heard anywhere around the world, no more people believe in being good, going for prayers and so on.
The story has it that, Dajjal were thrown away in the 7th layer of the sky. It will try to dig through, and, everytime he reach the last layer, Azan will be heard and he will run back, closing all hole he made and run back to the 7th layer. And it will repeat, until the day no more azan being heard. The day when Dajjal reach the earth, when evil run this earth.
Of course other religion got their own story of course. So actually the end of the world will come.
But somehow I think 2012 will not be the year...