Enzyme-rich raw food diets and their positive effect on various diseased conditions in both humans and animals have been well documented throughout the world. The first major scientific paper on enzymes was published April 15, 1940, by Dr. Edward Howell, in "the Journal of the American Association for Medico-Physical Research." Dr. Howell is formally recognized as the discoverer of the vital role of enzymes in human nutrition. He pioneered more than 50 years of research and scientific experimentation with overwhelming evidence indicating that the primary cause of degenerative disease in humans is enzyme deficiencies exacerbated by enzyme deficient mothers passing on genetic deficiencies to their offspring. Numerous studies have documented that when captive or domesticated animals are fed diets similar to human diets common to industrialized nations, they develop diseases similar or identical to human beings. In the early 1930's, and over the following 25 years, Francis M. Pottinger, Jr., M.D. conducted studies on cats using two diets. One diet consisted of two-thirds raw meat, one-third raw milk and cod liver oil. The second diet consisted of two-thirds cooked meat, one-third raw milk and cod liver oil. Studies revealed the following:

Multiple generations of cats on the raw meat diet were healthy. They had adequate nasal cavities, excellent tissue tone, good fur with little shedding, and no facial deformities. The calcium and phosphorous content of their bones was consistent. Their internal organs developed and functioned normally. Throughout their lifespan they were resistant to infections, fleas and other parasites. They were free of allergies and miscarriages were rare. Litters averaged five kittens, with mothers experiencing no difficulty nursing.


Multiple generations of cats on the cooked meat diet were not so healthy. They had many variations in facial bone and dental structure. Their long bones tended to be increased in length and smaller in diameter, showing less calcium. In the third generation, some of the bones were as soft as rubber. Other indications were heart problems, nearsightedness, farsightedness, underactivity or inflammation of the thyroid gland, infections of the kidney, liver, testes, ovaries and the bladder, arthritis and inflammation of the joints, inflammation of the nervous system with paralysis and meningitis. Infections of the bone appeared regularly, often appearing to be the cause of death. By the time the third generation was born, the cats were so physiologically bankrupt that none survived beyond the sixth month of life. Cats on the cooked meat diet were more irritable. There was evidence of role reversal, with female cats becoming the aggressors and male cats becoming docile and passive, either acting perverted or showing no interest in sex. Some females were dangerous to handle. Increasingly abnormal activities occurred between the same sexes. Vermin and intestinal parasites were rampant. Skin lesions and allergies were frequent and progressively worse from one generation to the next. Pneumonia and empyema (accumulation of pus) were principal causes of death in adults, with diarrhea, followed by pneumonia, the cause of death in kittens.

Females frequently had ovarian atrophy and uterine congestion. Males often failed to have active sperm development. Spontaneous abortion in pregnant females was about 25% in the first deficient generation, increasing to about 70% in the second generation. Deliveries were difficult, and many females died in labor. The mortality rate of kittens was high. Some mothers failed to lactate. Many failed to become pregnant, and those that did had difficulties. The average weight of kittens was 16% less than those born to mothers raised on a raw meat diet.

When cats of the cooked meat-fed first and second generation groups were returned to a raw meat diet, it took about four generations to recover a state of normal health.

Improvement in resistance to disease was noted in the second generation, with allergic manifestations persisting into the third generation. By the fourth generation, most of the severe deficiency symptoms disappeared, but seldom completely. Once a female cat was subjected to a deficient diet for a period of 12 to 18 months, her reproductive efficiency was so reduced that she was never able to give birth to normal kittens. Only when the kittens were put on an optimum diet did a gradual reversal and regeneration take place.