I just don't understand,why she still want to find "creator" of human meanwhile she still wearing cross

Enjoyed it very much. Free of any pre-conceptions of what the movie does have and does not have, and letting the philosophical agendas slide, this is a good movie. The intellectual scope of it is extremely limited, but the narrative scope is epic. The only problem is that while the scope is impressive, the inability of the script to satisfyingly answer some of the basic questions is frustrating. I'm going to give it the benefit of the doubt though; the sequel damn well better provide more concrete stuff. In fact, if this is the first of a two- or three-parter, and if the sequels deliver, I think the series has the potential to go down as a great. Not as a great intellectual sci-fi, but as an epic space adventure/horror franchise... I must admit, there is potential.

Plus I can see the sequel being better in terms of the characters. This one has way too many characters, 17 is just too many unless you plan to kill lost of them at the beginning and focus on the remaining few. Captain Janek is a really cool character, and is really the real hero in this, but he's just too underwritten. Same goes for Vickers. I actually liked her a lot, because she's hot and she emanates quite a bit of Ripley. By the end of the movie with most of the characters dead, the sequel should be able to focus more on just a few.

Okay so the bio-weapon outbreak occured in the Engineers spaceship that the Prometheus's crew found when they 1st landed on the planet.

In the Engineer spaceship, all the engineers was found dead except for one survivor (who later died after got tentacle rape-ed by Shaw's octopus baby).

Then at the ending, David offered Shaw for his help to seek another engineer spaceship because he mentioned that there are also a few spaceship similar to the one they found. And then we saw another engineer spaceship fly to the space with probably Shaw and David in it.

My 1st question is, did ALL the engineer spaceships in the planet had occurred the same outbreak same as the 1st engineer spaceship that the crew encountered? Because I found it funny that they required a lot of time to figure out what happened on the 1st spaceship but then it just took 1 minute for both Shaw and David to infiltrate another spaceship and fly it like nothing happen.

2nd question, if there's already an outbreak on the planet, why the heck that no help comes from the engineer's home planet to rescue. I mean, they are the superior race that monitor all life in the universe and yet they didnt sent any rescue team when outbreak occured. I mean, its look funny when the planet is abandon for 2000 years whilst nobody from the engineer's home planet found it strange like "why is it no one from our military base havent given any reports?"

I'm a fan of the Alien series, even the 3rd and the 4th movie, but not the AvP crossover series. So, I guess I'm easy to be pleased by Prometheus, it met my expectation except for the sci-fi horror elements that the Alien (1979) famously introduced ... maybe we're too jaded already, not easily shocked anymore.
It's kinda like a remake of the 1979 Alien. I watched it again back at home after watching Prometheus in cinema.  The 1st Alien movie only showed like maybe 15mins of scenes inside the Derelict alien spacecraft and the Space Jockey; the rest of the movie is inside the human spaceship playing hide and seek with the Xenomorph alien.
So, Prometheus' links to Alien is exciting to watch especially when the former expanded upon the discovery aspect of the Space Jockey and its ship, plus injecting a bit of creationism discussion.  But Ridley Scott isn't known for making abstract artistically ambiguous intellectual movies such as 2001:Space Odyssey, The Fountain or The Tree of Life; so the questions Prometheus posted could be straightforward and easily revealed in the sequels.  The contribution of creator/head writer of Lost tv series, as co-writer of Prometheus, could be seen here for its numerous unanswered questions, but most of them are minor and could be answered with external info; hopefully the sequels won't drag the major questions too long (as with Lost).  The only question I wanted to know the answer to, now is ....