the downside,

like ICQ where it will save ur 'current setting' like u just click disable 'typing sound' will not be save as the shutdown sequence take about 5 sec on a P4 1.5ghz etc etc,

others like winamp or other player will not able to save 'current playlist' as when the next time u on ur pc, the playlist will follow the one b4 the changes made(the session b4 the last one).

some torrent manager program are affected, like newly added torrent disappear due to not saved, or missing dl (u actually dled up to 99% and it revert back to 75%) etc etc