Gears OF war 2!!!
hahahaha

But I have to say...
What about Battlefield: bad Company?

90% destructive enviroments?
This game is gonna redefine FPS.

I say they should win.

GTA 4 was a good game, but it didn't really live up to my expectations(I finnished the game in 2 days mind you..)
MGS4 is gonna be great, but they have never won GOTY before (i think) cause MGS is more towards story telling and about epic movie momments.