If you want the whole subject (the spider) to be sharp, you have no choice but to use smaller aperture(big f number), maybe f11 or f16 would be good enough. Then reduce your shutter speed to get the correct exposure.
However, if shutter speed too low, your subject might be blur unless it keep still and not moving around.
If that the case, then you can up your ISO, so that your shutter speed can be faster.