just done beaten Lilith using Necromancer, when it aerial-ing the bomb, i have a skill to immune damage for 3 secs, and after that slowly slowly kill it..
not sure about rogue, maybe theres a guide in YouTube on this..

Finally win the game!! Damn epic battle. I swap my amulet with the beginner vigo amulet and at the end lilllith corner me with 5℅ health. The immune bubble came up and just spam my highest damage combo skill to kill her