Middle back seat is furthest from side impact, therefore safest from a car ramming you from the side. However, there are other issues to consider before assuming that middle back seat is the best choice in your car.
As I said before, your baby is safest in a carseat that is installed CORRECTLY. Middle seat often does not have LATCH or isofix. Some middle seats don't even have a seatbelt, or has only a lap belt, no shoulder belt.
If there is no shoulder belt, then it is NOT safe for even an adult to use the middle seat. If there is no belt at all, there is no way you can install a carseat there!
Let's say your middle seat has only a lapbelt, like my Myvi. If your carseat allows an installation with lapbelt only, then IF you can get a tight install with the lapbelt, then your carseat can gain the added advantage of being furthest from a side impact. Because my old Combi Coccoro enabled me to use lapbelt only, I could install in the middle seat. My Combi manual even instructed that if the Coccoro was installed on a side seat, no one should seat in the middle seat next to the Coccoro! So by installing my Coccoro in the middle, not only did I give extra protection from side impact to my baby, I was able to have two shoulder-belt seats for adults to seat safely beside my baby (admittedly it was a squeeze for them).
More links to choosing position of your carseat:
http://thecarseatlady.blogspot.com/2010/06...-be-riding.htmlhttp://carseatanswers.com/which-seat-is-sa...babys-car-seat/https://answers.yahoo.com/question/index?qi...30102652AAN0z9mInstalling in center seat with LATCHTo ascertain how secure your carseat is, compare how you've installed it to what the carseat manual says. Then try to move it where it is secured. It should NOT move more than an inch, up down sideways any way, at the area where it is secured by isofix belt or seatbelt.
Thanks for the pointers! Indeed, it is very informative.