I'm of the opinion that having any interest in anime, model kits, manga, and so on, has nothing to do with a person's chances of going into a relationship with the opposite gender.

I'm a bit of an Otaku myself, with my Gundam models and a considerable amount of Anime, but am quite happy with my love life (before you ask; Yes, it's with a real-life human female). So to answer your question, YES, girls DO accept Okatus' as partners.

But of course there's always a catch. Would you be as (or more) dedicated to your significant other as you are with your Otaku-ism? I think I can speak for both genders when I say that nobody is going to be thrilled with an Otaku/Fujoshi that consistently forgets your birthday because they are waiting for new anime releases....