I guess if you give directly large amount of K+ to the smooth muscle may help the muscle to get depolarized faster...and result in "large contraction"....I guess this will lead to muscle spasm to your smooth muscle organs?!

Yup. The key is depolarize faster due to influx of large amount k ions into the sarcolemma. The potential will reach threshold faster and action potential will be generated in higher frequency therefore continuos contraction will be achieved.ca cycle is for cross bridging for contraction. That's why i guess muscle spasm may occur. Correct me if im wrong.

I think it's depends on type of microorganism...if the pathogen is bacteria normally presented with WBC cast in the urine....Nitrite is due to present of pseudomonas aeruginosa with nitrase which can convert the nitrate to nitrite...or even direct detection of bacteria in the urine.....

This post has been edited by MBBS siang: Aug 8 2011, 02:14 AM

pseudomonas is the most common bacteria for nosocomial UTI....

This post has been edited by MBBS siang: Aug 9 2011, 01:16 AM

Oh I see....because during urinary system...my lecturer list pseudomonas as one of the commonest causative agent as nosocomial UTI....her name is DR rosni...."Pseudomonas aeruginosa,Disease: common cause of cystitis and pyelonephritis; higher incidence in hospital and nursing home patients,Epidemiology: one of the most common nosocomial pathogen" I quote this from my lecture notes.....

Limeuu...I'm entering clinical years....so far as what I know something I had learned from pre-clinical years is actually not that correct as the statement I made above is a proof...is there any advice to me during my clinical attachment because I really want to be a competent doctor in future but not a killer......To be honest I learned quite a lot from this forum....

This post has been edited by MBBS siang: Aug 9 2011, 04:38 PM