This is done by simply taking a small amount of blood from the mother to check for any chromosomal defects or abnormalities. Is that possible? Is Down syndrome only occurred by genetic inheritance?

My wife did it & it gave her a piece of mind throughout the pregnancy.

Private clinics usually price their package above RM 2k.

If the price is of concern, can try NIPT by GGA. My wife did the PLUS package for RM 1.2k.

https://www.ggasia.com.my/services/nipt-non...renatal-testing

What does it called for those doing in hospital with lower charges around RM200-400? The accuracy is lower around 60-70%.Other than that, what are the diffeences?

I brought my wife to private clinic for checkups so honestly idk about public hospital on this matter. My guess is their package is basic which covers just the 3 basic Trisomy T13, T18, T21. You may want to cross check their offerings in detail.

Actually it is necessary.