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 Use of Ivermectin against Covid-19, LETTER TO NOOR HISHAM

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funnyTONE
post Apr 12 2022, 11:35 AM

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QUOTE(nasiputih @ Apr 12 2022, 11:23 AM)
any news about ivermectimah? wasnt there a KKM study started in Jun2021?
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Basically, it works.
But its a generic medicine, so there is no profit to be made.
Hence, we see Pfizer is making their own antiviral pill.
Give it a different name, thus can print money again.

Malaysia receives first shipment of Pfizer's, Paxlovid anti-viral pills
funnyTONE
post Apr 12 2022, 12:11 PM

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QUOTE(desmond2020 @ Apr 12 2022, 11:44 AM)
biar betul, where is your source of information that said it work?
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I read.

Ivermectin works by inhibiting 3CL protease enzyme so the virus can't bind and replicate.
There are numerous research papers done about it.
Several countries in fact, uses ivermectin as a form of medical treatment for covid patients (brazil, japan, India, etc).

Here is one of the study:

user posted image
Ivermectin exhibited complete inhibition of SARS-CoV-2 3CLpro enzymatic activity

To compare, I'll paste the same function of Pfizer's new antiviral drug and how it works:

user posted image
Pfizer’s Novel COVID-19 Oral Antiviral Treatment Candidate Reduced Risk of Hospitalization or Death by 89% in Interim Analysis of Phase 2/3 EPIC-HR Study
funnyTONE
post Apr 12 2022, 12:13 PM

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QUOTE(Namelessone1973 @ Apr 12 2022, 12:05 PM)
What do you mean it works?

There are still people who believe in Ivermectin?

How much back stock you still have?  whistling.gif
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explain why would pfizer's antiviral work then?
funnyTONE
post Apr 12 2022, 12:16 PM

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QUOTE(desmond2020 @ Apr 12 2022, 12:12 PM)
we are talking about KKM study lah. Why shift the goal post?

Berdasarkan hasil kajian I-TECH, ivermectin tidak disyorkan untuk dimasukkan ke dalam garis panduan rawatan COVID-19 sedia ada kerana ivermectin tidak mengurangkan risiko penyakit COVID-19 tahap teruk. KKM menyarankan agar ivermectin hanya digunakan dalam kajian klinikal dengan pemantauan. Keputusan I-TECH juga selari dengan kajian berskala besar seperti IVERCOR-COVID19 dari Argentina dan TOGETHER dari Brasil yang tidak menyokong penggunaan rutin ivermectin dalam amalan klinikal rawatan COVID-19. Pasukan kajian I-TECH bercadang menghantar data kajian tersebut untuk diterbitkan di dalam jurnal peer-reviewed bagi memberi maklumat tambahan kepada kajian-kajian ivermectin termasuklah meta-analysis.

Kenyataan penuh Ketua Pengarah Kesihatan, Tan Sri Dr Noor Hisham Abdullah
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kek, did I mention KKM?
I'm quoting a research paper as well.
No one is shifting the goal post.

KKM study isn't even peer reviewed. lol!
funnyTONE
post Apr 12 2022, 12:16 PM

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QUOTE(Starbucki @ Apr 12 2022, 12:16 PM)
Any sos to say it works? And why do you say paxlovid = ivermectin?
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read my post above.
funnyTONE
post Apr 12 2022, 12:18 PM

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QUOTE(blindmutedeaf @ Apr 12 2022, 12:16 PM)
please go ahead with the ivm.... i will stick back to WHO recommendation and thus less people compete to buy
many thanks
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Its a generic medicine way past its 20 years patent period.
Thus, doesn't make profit to pharmaceutical companies.

This is why pfizer creating the same antiviral medicine, but with a different name so they can patent and make exclusive manufacturing rights to it.
funnyTONE
post Apr 12 2022, 12:19 PM

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QUOTE(desmond2020 @ Apr 12 2022, 12:17 PM)
if you are not doctor and know jackshit about medicine, why don't you leave the job to professional at KKM?

Berdasarkan hasil kajian I-TECH, ivermectin tidak disyorkan untuk dimasukkan ke dalam garis panduan rawatan COVID-19 sedia ada kerana ivermectin tidak mengurangkan risiko penyakit COVID-19 tahap teruk. KKM menyarankan agar ivermectin hanya digunakan dalam kajian klinikal dengan pemantauan. Keputusan I-TECH juga selari dengan kajian berskala besar seperti IVERCOR-COVID19 dari Argentina dan TOGETHER dari Brasil yang tidak menyokong penggunaan rutin ivermectin dalam amalan klinikal rawatan COVID-19. Pasukan kajian I-TECH bercadang menghantar data kajian tersebut untuk diterbitkan di dalam jurnal peer-reviewed bagi memberi maklumat tambahan kepada kajian-kajian ivermectin termasuklah meta-analysis.

Kenyataan penuh Ketua Pengarah Kesihatan, Tan Sri Dr Noor Hisham Abdullah
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we both are not doctors.
I've given factual proof of research papers. but you choose to ignore it anyway.
apa lagi you mau bukti?

My statement lies true unless proven otherwise.
Ivermectin works.
funnyTONE
post Apr 12 2022, 12:26 PM

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QUOTE(Namelessone1973 @ Apr 12 2022, 12:15 PM)
Why not? They are pharmaceutical company isn't it? Isn't it their biz to research and release drugs to treat diseases?

More importantly, Ivermectin is not even an antiviral drugs.
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So who do you think created ivermectin in the first place?
It was researched and created in japan by drugs company.

So they both have the same purpose and the same origin. That was my point in my earlier post.
Both ivermectin and pfizer's antiviral drug works exactly the same.

So why you believe in a new drug but not a 50 year old drug?
funnyTONE
post Apr 12 2022, 12:28 PM

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QUOTE(blindmutedeaf @ Apr 12 2022, 12:24 PM)
i still don't think IVM is Pfizer antiviral

left is pfizer chem struc and right is ivm... how i see also not same... any chem eng here?

user posted image
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of course they can't be exact copy.
But the way it works is the same.

Inhibiting the 3CL prolease enzyme.
funnyTONE
post Apr 12 2022, 12:38 PM

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QUOTE(desmond2020 @ Apr 12 2022, 12:28 PM)
ivermectin is antiworm drug dude

non of its clinical trials involve use as antiviral

damn son.
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New applications for different drugs always happen all the time. Doesn't mean it couldn't be used for other treatment.
Here's a medical journal for thought:
user posted image

QUOTE
The 2015 Nobel Prize in Physiology and Medicine was awarded to William C. Campbell and Satoshi Ömura for their discoveries leading to ivermectin [1]. In addition to its extraordinary efficacy against parasitic diseases, ivermectin continues to offer new clinical applications due to its ability to be repurposed to treat new classes of diseases. Beyond its invaluable therapeutic role in onchocerciasis and strongyloidiasis, an increasing body of evidence points to the potential of ivermectin as an antiviral agent.


Ivermectin: an award-winning drug with expected antiviral activity against COVID-19

And this is my personal opinion:
Its not profitable for drug companies to further research this. Its better for them to make a similar type drug and patent it for profit.

Kinda funny why KKM didn't bother doing a clinical study on pfizer's new antiviral drug but had it ordered for us. Do you think that is good enough?
funnyTONE
post Apr 12 2022, 12:45 PM

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QUOTE(blindmutedeaf @ Apr 12 2022, 12:37 PM)
my thoughts are 50 years ago, there were no covid that's why it is C-19

just like hepatitis B virus was discovered in 1965, so you are telling me to use the drug before 1965 to treat B.... can it really work?

is our equipment getting more accurate or there is more virus on Earth now? what do you think?
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Good question, but its beyond my expertise.
Luckily however, we have abundant of information and good sources to read up about it.
There are some things I could comprehend on a simple level that makes sense.
I don't blindly believe in any medicine, but a research study in vivo does help me see a clearer picture.

Killing a virus has many ways.
Fire kills anything.
Acid corrodes carbon-based materials.
But doesn't mean its the best way of killing a virus.
I totally agree that newer technology pave the way for better medicine and better treatment. But to know for sure if an old medicine still works today is to continue doing researches and study on it. Unfortunately, clinical trials costs millions and are usually funded by private companies. We can't always expect our government to fund a million dollar study and expect nothing (financially) in return. Would be nice if we could.
funnyTONE
post Apr 12 2022, 12:48 PM

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QUOTE(karwaidotnet @ Apr 12 2022, 12:34 PM)
i laugh.... kek

not the same. but work the same. ok.

if this statement does not proof you're a troll. i dunno what else is...

keep feeding the troll....
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feel free to prove me otherwise then.
Surely there must be a research study out there that proves ivermectin doesn't work against covid virus.
funnyTONE
post Apr 12 2022, 01:06 PM

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QUOTE(blindmutedeaf @ Apr 12 2022, 12:41 PM)
expected is the keyword boss...
it just like car was meant to be a transport, not a mass killing machine but people still can use that to drive into crowds
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hahaha, nice.
So you're saying the word expected is not convincing/good enough?

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