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 Covid Therapeutics trials Interim update, bad news, WHO Solidarity trials

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SUSlijor the great
post Apr 14 2021, 01:13 AM, updated 3y ago

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Trial drugs little to no effect on 28 day mortality rates or hospital duration

QUOTE
In just six months, the world’s largest randomized control trial on COVID-19 therapeutics has generated conclusive evidence on the effectiveness of repurposed drugs for the treatment of COVID-19.

Interim results from the Solidarity Therapeutics Trial, coordinated by the World Health Organization, indicate that remdesivir, hydroxychloroquine, lopinavir/ritonavir and interferon regimens appeared to have little or no effect on 28-day mortality or the in-hospital course of COVID-19 among hospitalized patients.

The study, which spans more than 30 countries, looked at the effects of these treatments on overall mortality, initiation of ventilation, and duration of hospital stay in hospitalized patients. Other uses of the drugs, for example in treatment of patients in the community or for prevention, would have to be examined using different trials.

The progress achieved by the Solidarity Therapeutics Trial shows that large international trials are possible, even during a pandemic, and offer the promise of quickly and reliably answering critical public health questions concerning therapeutics.

The results of the trial are under review for publication in a medical journal and have been uploaded as preprint at medRxiv available at this link: https://www.medrxiv.org/content/10.1101/202...0.15.20209817v1

The global platform of the Solidarity Trial is ready to rapidly evaluate promising new treatment options, with nearly 500 hospitals open as trial sites.

Newer antiviral drugs, immunomodulators and anti-SARS COV-2 monoclonal antibodies are now being considered for evaluation.
Attached File  2020.10.15.20209817v1.full.pdf ( 1.53mb ) Number of downloads: 0


This post has been edited by lijor the great: Apr 14 2021, 01:27 AM
JohnL77
post Apr 14 2021, 01:36 AM

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AMDK USD 3,000 per round Remdesivir doesn't work? Boh kor leng!


miromiro
post Apr 14 2021, 09:22 AM

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Covid variant become more and more better
edmund_yung
post Apr 15 2021, 12:26 PM

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Any news on cheap Ivermectin?
SUSlijor the great
post Apr 15 2021, 12:39 PM

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QUOTE(edmund_yung @ Apr 15 2021, 12:26 PM)
Any news on cheap Ivermectin?
*

JohnL77

JohnL77
post Apr 15 2021, 12:44 PM

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QUOTE(edmund_yung @ Apr 15 2021, 12:26 PM)
Any news on cheap Ivermectin?
*



edmund_yung
post Apr 15 2021, 12:53 PM

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thanks JohnL77 Do you have any idea what's the best way to obtain it in Malaysia? Now that KKM allows covid-19 patients to quarantine at home, I'm thinking to keep some stock in case I need to use it to manage my own illness.
JohnL77
post Apr 15 2021, 12:58 PM

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QUOTE(edmund_yung @ Apr 15 2021, 12:53 PM)
thanks JohnL77 Do you have any idea what's the best way to obtain it in Malaysia? Now that KKM allows covid-19 patients to quarantine at home, I'm thinking to keep some stock in case I need to use it to manage my own illness.
*
No.

I think it's best to consult a doctor.

 

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