Sure enough. Clean install Win 10 about 30 GB. After load all needed software top out about 60 GB used. For the longest time I was using 120 GB SSD for my PC, no problem. Only must make sure to plug in USB when have things to save like videos and images.

One issue is that the speed of 120 GB usually the slowest of the family of SSD. But still much faster than HDD, so YMMV.

4 GB RAM also no issue, especially since you use SSD when ever there there is swap file going on.