M.2 is a physical form factor - M.2 can be used with SATA/PCI-E interface.  Check your motherboard manufacturer on which interface the M.2 slot can support.  Some boards may support PCI-E M.2 and some boards may only support SATA M.2

Any M.2 NVMe SSD will do
But since your motherboard does not have an M.2 slot, you will have to buy an add-on card so that you can install the M.2 NVMe SSD into the PCI-e slot

Something like this:
https://shopee.com.my/%F0%9F%92%93PCI-Expre...7818.2240610033

Downside: If you use NVMe SSD in your ITX motherboard, you can no longer install a discrete GPU into the motherboard because your motherboard only has a single PCI-e slot