Do not give this game to children. Seriously. Play with them, maybe. This is not a game for kids.
Go for the deluxe edition with the artbook if you are the type that wants to know more about the characters in the game. Contain spoilers so don't read it until you finish the game.
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Gwen The deer: yeah she kill herself cause most of the time her parents never pay attention to her, especially her father(80% Correct. Didn't kill herself, not directly anyway. Wanted to but was stopped the same way in game. Item given to Stella is a clue on cause of death.)
Summer the snake: I feel like she is battling depression (the dragon), just like her father, she could not run away from her fate, and she accept to come peace with it at the end.(90% correct. Physical condition, not mental. What happens to the dragons is a clue.)
Alice: my dear alice, my poor poor alice,she suffer from Alzheimer's disease, or dementia you can call it, she really me so sad when she start to mistaken stella as her daughter.(100% Correct)
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Gwen: i check the item she left for me, hmm must be die from fire accident(The thing she does while idling that involves this item. Known side effect of that activity. Also reason for suicide attempt.)
Summer: oh god, CANCER ?! (Yup)
Alice: it is very clear cut near the end of her quest for me cause my late grandmother passed away like that (around 2007, more or less), thus I felt it personally, and I also recently listened to one experimental album dealing with dementia
Also currently my companions are:
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Gustav, Alto(Astrid?) and recent got her Giovanni
Multiple ways of dying. The one or more of the Everdoor farewells is bound to affect you sooner or later.