Let's fix some of the comments above...as well as the question asked.
Usually an SSD in a notebook is in M2 form factor, and the SSD is changeable. Say Asus ROG GL552 supports M.2 2280 (22mm tall, 80mm long) in PCIe x 4 mode, means strong SSDs such as Samsung 950 PRO M2 NVMe or Kingston PCIe SSD can be installed into this laptop as long as it follows the specification. All of these are expensive SSDs.
Some notebooks will have the M2 slot which supports both SATA interface and PCIe x 4 mode, say MSi GL62, which means it supports all M2 SATA, M2 PCIe and M2 NVMe. M2 SATA is a cheaper variant of M2 SSD because it runs slower than the latter ones, but is already fast enough considering you're not doing heavy rendering, heavy video editing and such.
Thirdly, check your specs of the notebook. Does it support dual drives? Usually, again, notebooks that support dual drives will have a 2.5" HDD, and a M2 SSD. SOME notebooks (slim/ultraslim type) will omit the 2.5" HDD because it adds the thickness of a laptop, leaving only an M2 slot, some even soldered them to the motherboard. Choose wisely, depends on your preferences.
Usually, again and again, running SSD+HDD will not affect the speed of each other, by means it will not make the other to run faster/slower/noisier etc etc vice versa. For instance the image below:
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Both runs at different places. In your PC, it will detects as 2 different drives. HDD is for storage purpose for example Spotify songs cache, Steam games and such, while the SSD would be your primary drive, running the OS as well as software which you always use such as developing tools, Steam client, chrome etc. Setting as primary drive between the two can be done in BIOS, but the distributors would have already set the SSD as the system drive instead of HDD.
This post has been edited by lolzcalvin: Nov 28 2016, 03:28 PM