At 1:50... why do I get a feeling The Avengers are "no more" or rather "not available anymore".

Also, Happy seems to be running around with Spidey instead of Tony Stark - - did Tony Stark... not make it?    My idea is that Tony Stark retired and is living a recluse after Endgame.

And Nick Fury doesn't look too pleased, maybe that's just how he looks all the time.

I also get the vibe of a "Young Avengers" team brewing. 
This is after Avengers Endgame, the first post-Endgame MCU film.

I'm pretty sure whatever happened to the Avengers in Endgame will carry forward in this film... it would be weird if it was happening parallel with it or BEFORE the events of Endgame.

Yeah, seems like Aunt May has embraced Peter's Spidey and  loving the attention 

As expected MJ and Peter's relationship will blossom and MJ will be dolled up instead of her washed up look in Homecoming, a really unique take on the character MJ, tampering with our expectations from the first film and that's nice.