high five! haha i was thinking if i should farm the fire dungeon to awaken my fire inugami that i just got too   

evolve!!!
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My current runes setup on him is like this :
1: +6 Energy Rune [3 stars] : ATK +37, Effect RES+4%, Effect ACC+3%
2: +6 Energy Rune [3 stars] : HP +16%, CRI Dmg+4%, CRI Rate+2%
3: +6 Energy Rune [3 stars] : DEF +37, CRI Dmg+4%, CRI Rate+2%
4: +6 Energy Rune [3 stars] : HP +16%, ATK+9, HP+108
5: +6 Energy Rune [3 stars] : HP +550, SPD+5, HP+5%
6: +6 Energy Rune [3 stars] : HP +550, CRI Dmg+6%, HP+2%

Final stats for my fire hellhound in 3 stars is :
Lv 25/25
HP 2490+3302
ATK 271+46
DEF 153+37
SPD 109+5
CRI Rate 19%
CRI Dmg 64%
Effect RES 19%
Effect ACC 3%

Couldn't hunt the Hell mode for the 1st map, so couldn't get any 4-6 stars runes.. Any recommendation which rune can keep, which needs to be replaced?

just my personal preference, hound hp is not high, so equipping hp rune for him is quite wasteful since % based rune only applies to the base stat, not the stat after adding rune. My hound use the following setup.

Slot 1: Blade +atk
Slot 2: Fatal  +atk%
Slot 3: Fatal  +def
Slot 4: Fatal  +crit%
Slot 5: Fatal  +hp
Slot 6: Blade +atk%

As suhuann mentioned, rune 1,3,5 is fixed stat, so dont bother farming lol.

guys, i need some input in building a defensive team for arena purpose, my current glass cannon team is just being an easy target for everyone. Below are my summons, there is a wind warbear and water hound below and that is it. I dont't mind even if the team relies on my tower to do the job, i just don't wanna get targeted so often lol