I don't think you have PBA, so that is a relief for you.

PBA tends to happen in people with nerve disorders like muliple sclerosis
and amyotrophic lateral sclerosis, Parkinson's disease, strokes and brain injury.

http://en.wikipedia.org/wiki/Pseudobulbar_affect#Causes

https://www.pbafacts.com/



Very likely, from this study, you may have insufficient amounts of the
biochemical called noradrenaline in your system, leading to a condition
called Crying Proneness (CPR).

CPR is different from Pathological Crying (PLC), which happens secondary
to a brain injury or disease like stroke, Alzheimer's or Parkinson's. PBA
falls under PLC.

This appears to be why they noted that that the SSRI class of antidepressants like
Prozac and Zoloft, which increases the amounts of serotonin in your system and usually
helps PLC, does not help CPR, but the other class called SNRIs, which also increases
the amounts of noradrenaline in addition to serotonin, does.


Examples of these SNRI drugs are :

Venlafaxine (Effexor)
Duxoletine (Cymbalta)
Mirtazapine (Remeron)



Evidence for Involvement of Central Noradrenergic Activity in Crying Proneness

" Indications of noradrenergic involvement in PLC are provided in short
reports where the SNRI drugs venlafaxine, mirtazapine or duloxetine were
used successfully in patients with PLC who failed to respond to SSRIs. "

http://neuro.psychiatryonline.org/article....rticleID=181295


My preference would be mirtazapine, which causes the least side effects
and is quite safe even when overdosed.

Mirtazapine is a tetracyclic class of antidepressant, considered an improvement
over the older tricyclics in terms of effectiveness and safety towards the heart.

Strictly speaking, mirtazapine is not an SNRI, but a NaSSA (Noradrenergic and
Specific Serotonin Antidepressant).

http://en.wikipedia.org/wiki/Noradrenergic..._antidepressant


It is a modified form of the first-generation tetracyclic, mianserin (Bolvidon).


" Mirtazapine is not considered to have a risk of many of the side effects
often associated with other antidepressants like the SSRIs, and may
actually improve certain ones when taken in conjunction with them. "

http://en.wikipedia.org/wiki/Mirtazapine#Side_effects


You may wish to discuss your condition with a doctor, preferably a psychiatrist.
You could print out the above study to discuss it with him, and possibly
go on a short course of low-dose mirtazapine to see if if helps you.


http://www.toddlertime.com/med/remeron.htm

http://www.aafp.org/afp/1999/0101/p159.html





This post has been edited by Tham: Jul 30 2013, 12:10 AM

In this study, mirtazapine worked for this woman, who had PLC after a stroke,
after two SSRI drugs, citalopram (Celexa) and sertraline (Zoloft) failed to help her.


Mirtazapine treatment for pathological laughing and crying after stroke.

http://www.ncbi.nlm.nih.gov/m/pubmed/16239769







This post has been edited by Tham: Jul 30 2013, 12:28 AM