I'm really really sure. S4.1 is the one for u.

I'm using it now, no way R501MKII can come close to S4.1 in term of clarity.

60W 6.5inches subwoofer is enough for a small room.

U can goto Edifier showroom to test it out. Both speakers u mention are there waiting for u to test.

I can say R501MKII bass sounded more deep and booming, coz 8inches subwoofer.

But S4.1 subwoofer is 60W compare to R501MKII subwoofer 30W??.

So, S4.1 bass sounded more hard n solid.


By the way, S4.1 satelites sound much much more better than R501MKII satelites.

So for movie n gaming R501MKII is a good performer.

S4.1 is more balance toward MUSIC, movie n gaming.


Both speakers will not disappoint u.


Lastly,

S4.1 is a highend product of Edifier, while R501MKII is a midrange product.

R501MKII come with a remote control, while S4.1 come with a wired remote.