yes u can! i own 3 of those controllers in xbox 360 package not the pc package version as it is cheaper and it all work fine on my pc, the driver can be downloaded easily.
if u r asking about the wireless one thn u need to get the wireless dongle either by getting the pc packaging version of wireless controller or just get the dongle somewhere.

This post has been edited by pingy_ping: Aug 28 2012, 12:30 PM