hi to all sifus i i'm currently running on:

intel core 2 duo e4600 2.4ghz @ 200mhz x 12multipliers default
ram 2gb ddr2 800 mhz x2
mobo gigabyte p35-ds3l

im planning on to oc my pc between 2.7ghz ~ 3ghz
1. is it safe that if i tweak my clock speed to 400mhz and lowering the clock multiplier to match the ram speed?
2. lowering ram speed to match the clock speed (more multipliers) or it isn't necessary? (in terms of performance)

thanks if anyone could help me on this