I don't think there's any relation to HDD but you can use tools below to help you. (Google them)
HDDScan (Detect almost every interface, USB supported)
Speedfan (Almost all temperatures, SMART)

Use them to check the SMART attributes, look for keyword "sectors count", if there's some numbers in the RAW then you might need to watch out.
If you don't know, just paste your screen shot here and some guru may be able to help you identify the issue.

From the SMART attributes,  you should keep a look out for the CRC errors, it has the exclamation mark there so that's the attribute that you should look out for.
I see that it has 1 CRC error, means either the controller, interface (cable, plug, socket) having issue, either way if you didn't see this increase over time then it might just be coincident so not much to worry about your HDD.
Perhaps you can open another thread at Technical Support or Q&A, list your HiJackThis result and see if any guru can help you identify the cause of your Diablo FPS issue.
HiJackThis can be downloaded here... www.filehippo.com/download_hijackthis/
Slower FPS in gaming does not necessary to be in 1 area, it could be anything.

and maybe the GC driver doesn't match the game.
The diablo 3 really gave me lots of headache due to its NON-STOP UPDATES & PATCHES.

Somehow after update the GC driver it can gave me GSOD when playing D3, while previous driver just make it black screen for few seconds at its worst.

mSata.....as i heard can be used to shorten the boot up time for those that did not have ssd

is better to buy a true hdd if for OS

typo....should be true ssd