Like many who said here before, no brand is the best brand. It really depends if your LO likes it or not.

My babygirl started off with medela for convenience because my wife uses medela breastpump. However, my girl had mild colic and we switched to Dr. Brown and straight away colic gone!

I've been using Dr. Brown ever since (My baby is 13 months now). I do agree that Dr. Brown is harder to clean as they have many parts (the tube insie etc).

Again, try out the brand you feel right for your LO first...if they are happy with the bottle, stick to it. There is no best bottles around. Just have to make sure it is bpa free.