Good for you Redzaril for taking the kittens in.
Yes, it is necessary to ensure that the kittens are dewormed and vacinated.
Vacination is necessary for the first 3 months and thereafter once a year.
This is to boost up the kittens immune system so that the body is strong enought to fight off diseases.
Deworming is also very important as worms in the tummy can cause a lot of sickness in a cat too e.g. skinny as the worms are eating all the nutrients, diarhea etc
Little things like vacination and deworming will save your kittens from getting serious illness thus saving you lots of $$$$. 
Next would be neutering when the kittens reach the right age.
Neutering would prevent unwanted pregnancies and kittens!

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Added on February 11, 2012, 11:46 am

Usually cats will groom themselves so not necessary to clean them up unless very dirty.
I too use wet tissue (for babies with no alcohol) for my daily cleaning in cats e.g. cleaning their ears, wiping their faces etc
Its very useful.