nope... it's a 2.1 forever... unless you buy a separate active center channel to work then it's a yes...

but if you are thinking of connecting S530D with a center channel like Aego M then it's a no

those are just number of speakers.

2.0 is best for music because music are produced in stereo (anything works in 2.0 actually... I watch movies with 2.0 setup and it's good enough)
2.1 is because some people just wanted subwoofer so the subwoofer existed for the thub thub bass
5.1 is for surround sound which is useful for movies because movies are normally in surround sound and music isn't

so yea... you can use 5.1 for music listening but why waste space when you can get better performance on what you need