Run away and do what? What is it that you can do alone that you cannot do with the support of your friends and family? And if you do not succeed, you run away again?

Some of us have too much pride to run. Whatever problems before us, we solve. Whatever problems we can't, we work around it. Whatever shit life throws at us, we take it on the chin and stand tall. Win, not turn tail and flee.

If it is a split from a business venture with your brother, then do it if it's necessary. But do keep in touch with your parents.