1) Removing the EFI fuse wont reset your ECU, removing your battery does (correct me if im wrong)

2)Highly unlikely that electrostatic from sitting on a car seat could fry your fuse. Semiconductors are sensitive to electrostatic, not not a 12A (or more safety feature)

3) If you lose a fuse, there are usually spares located in the fuse compartment itself, just in case you need a replacement.

4)When removing the fuse, pull it straight out, not wiggle it side to side.This way, your fuse socket wont get loosened by repetitively removing and reinserting it.