This one is different.

The Cleaner 2011 Portable:

http://www.moosoft.com/cleaner7/cleaner7_portable.zip

This is a specially compiled version of The Cleaner 2011 designed to run on USB thumb drives.
It has some limitations such as:
    * No connection to live news at startup
    * No auto-check for updates at startup
    * No Real-time scanner included
    * No Helper Service included, this may limit the ability to remove rootkits.
    * The Cleaner will not attempt to upgrade the program or check for program updates, database updates work as normal.
    * It is not suitable to be run off a CD/DVD-ROM, only a USB drive.