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 Inbreeding and Accelerated Evolution, prev: Incest, Inbreeding & Evolution

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lin00b
post Dec 20 2009, 09:43 PM

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while selective human breeding may produce offspring of superior quality;

1. our genetic knowledge is not good enough to ensure this "smaller, leaner gene pool" have a good enough defence against future desease.

2. humans are not mindless machine that act purely on logic. if your you dont like your partner despite s/he having the most compatible genetic material, you dont proceed.. and vice versa.

3. and no; while religious text may suggest inbreeding (starting population=few). this does not happen with evolution. as evolution is not discrete. during speciation, neighbouring branches are still fertile with each other and with the source branch, providing ample variation until the new species have a big enough population size.
lin00b
post Jan 5 2010, 12:33 AM

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does freedom of choice/human right include the freedom/right to marry your own sibling if both party consent?
lin00b
post Jan 7 2010, 09:01 PM

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QUOTE(Mesosmagnet @ Jan 7 2010, 05:33 PM)
Funny how everyone keeps insisting that our recessive genes are more likely to bring harm rather than good.

I'm not saying that they don't bring about harmful traits, but that's the way nature works. Go through a huge bunch of combination until it comes up with a good one to proceed on. Or am I wrong?

Another point to ponder on.. if inbreeding is bad.. then why are we not mating with apes? Humans all in some way related to each other, so we should not be mating among ourselves. And if you go back to a time when there were only a few humans, it is very very obvious that inbreeding did take place, and that is what probably allowed each ethnicity to develop unique likenesses to suit the way of life and environment. eg. Those in sunny countries developed skin to survive in such an environment, people in cold developed sharper noses to be able to breathe in colder air without damaging their inner nasal cavities. If we really look at each ethnicity unique feature we can clearly see evolution. Which very likely would not be present if we continually resisted inbreeding.

I look forward to a rebuttal statement. ^^

EDIT: thanks for the reading material. After reading that I would like to point out that the inbreeding that is being discussed here is not selective inbreeding, as in we do not get to choose which to keep which to be rid of, but rather let nature be the judge of what to keep and what to be rid of. And obviously I am not suggesting that we should ONLY practice inbreeding, as other humans also posses traits that makes a super elite human. And by incorporating them by cross breeding and removing unwanted genes through inbreeding the human race is likely to progress through evolution much faster. =P
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by saying "there are only few humans last time, therefore they inbreed" it shows you do not understand evolution.

understand this.

EVOLUTION IS NOT DISCRETE.

and at present, since human and ape are separate species, they will not produce any fertile offspring (if they produce any at all)
lin00b
post Jan 12 2010, 08:56 AM

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QUOTE(thesupertramp @ Jan 12 2010, 02:18 AM)
I disagree.

Modern medicine has increased human life expectancy by leaps and bounds. That, surely, must mean an increase in survivability? Living longer will allow a longer period for reproduction as well as nurturing the young. How can that not increase survivability?

Furthermore, many diseases can affect almost every human given the chance, regardless of how strong the individual is. And a car can hit anyone, even Arnold Schwarzenegger will need a orthopod when a bus hits him (or a funeral parlour).
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look at it this way, science and technology are the something like the "NEP of evolution" they artificially protect us. now, for any reason if these technology is removed from our daily lives, imagine how vulnerable we will be to the elements and disease.

some individual are more resistant to disease than others. some people seemed to catch whatever sickness thats the flavor of the month. others rarely even get a sore throat. and some community in africa is highly resistant to malaria. etc etc.


Added on January 12, 2010, 8:58 am
QUOTE(Dickson Poon @ Jan 11 2010, 11:39 PM)
But that's sexual selection - for intelligence and mental acuity - and that furthers evolution also.
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not really, if you look at male preference, it has gone from plump female circa 1500 to slim female circa 2000. so if there are evolution, where would the selection pressure be? towards plump or slim individuals? and you cannot tell what the preference will be at 2500. the period is also too short to produce any meaningful results

This post has been edited by lin00b: Jan 12 2010, 08:58 AM
lin00b
post Jan 13 2010, 12:43 AM

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QUOTE(Mesosmagnet @ Jan 12 2010, 04:13 PM)
user posted image

I came across this picture many times while doing some reading. This picture states the facts that a recessive deleterious allele will become dominant in offspring born of 2 carriers of the deleterious allele. But it seems to have removed the other possible outcomes.
Aa + AA = { AA, Aa, Aa } the assumption is that the deleterious allele is more likely to be passed on rather than the dominant beneficial allele? According to probability shouldn't the chances of offspring with AA and Aa be equal?
Aa + Aa = { aa } and where have the other possible outcomes gone? Aa + Aa = { AA, Aa }. Yet again in terms of probability the chances of producing offspring with Aa should be higher than aa and AA.

Now lets define a new diagram: (only inbreeding, no crossbreeding)

First Stage :
AA + Aa = { AA, AA, Aa, Aa }

Second stage :
AA + AA = { AA, AA, AA,AA }
Aa + Aa = { AA, Aa, Aa, aa }

Third stage :
AA + aa = { AA, Aa, Aa, aa } but if natural selection were to be present aa wouldn't get a chance to reproduce no? **
Aa + aa = { Aa, aa, aa, Aa }
**Over time, natural selection weeds deleterious alleles out of a population — when the dominant deleterious alleles are expressed, they lower the carrier's fitness, and fewer copies wind up in the next generation

Already by the 3rd generation we see that the AA individuals are more abundant than individuals with Aa and aa.
I am assuming that we can compute the outcome of genetic drift using probability.

Another point to ponder : what if there were a recessive beneficial allele? What outcome would we get then?
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A being the dominant allele will suppress the recessive a. so Aa while carrying bad genes, the bad quality is not express and the individual live a healthy life.

so as far as quality of life is concern, Aa and AA has no difference. while aa is catastrophic. in case of a large population, the chance of aa being expressed is significantly lower than AA or Aa as opposed to a small sample size of inbreeding.

as shown in the your example, by the third generation, 3/8 has aa. (1/8 at 2nd)

comparatively in crossbreeding, the chance of aa being expressed is significantly lowered.

not not neccessary all a is bad, there is a possibility that ou have some recessive genes that are good. but life prefer to err on the side of safety. its basic instinct. you prefer to take a risk if its to protect something you already have rather than to take a risk to get something that may benefit you.


Added on January 13, 2010, 12:51 am
QUOTE(Dickson Poon @ Jan 12 2010, 05:46 PM)
What is the basis of your assertion that male preferences have shifted from plump women to slim women?

Also if the time period of human history up to the present and five hundred years in the future is too short to produce any meaningful results in human evolution, then what's all the fuss about humans not evolving anyway? The time scale we are talking about would still be too short despite the technological advances and changes in human lifestyle.]
see difference from renaissance to present day

also

some article

now, i am not saying plump women are unattractive or vice versa, but society in general views slimness (hour glass) as the ideal female figure now, versus the plumpier version as the ideal 500 years ago.

there are numerous psychological and economical reasoning into why this happened, if you are interested in learning more.

yes, current age with medicine and technology is too short to produce any significance in evolution pressure, but if the current trend continues, we will see human as a species rely more and more on technology and medicine, and less on any evolution that occur (ie, the one that is more susceptible to illness get more or less the same chance to reproduce as the healthy one)


Added on January 13, 2010, 1:04 am
QUOTE(thesupertramp @ Jan 12 2010, 11:00 PM)
I still disagree. Humans have used medicine to treat themselves for thousands of years, possibly millions. Other animals have shown similar traits as well (dogs eating grass). Now, although Lamarckism is distinct from Natural Selection, it does play a significant role in a species's survival.

It is true that genetically our genes might not be "better" due to medicine, but the use of modern medicine can be equated to similar traits demonstrated by other primates, such as calling out when they see danger so that their entire group can flee. Thus, both forms can be said to provide evolutionary advantage to a species, but Darwin's evidence seem to suggest team work is more important. In The Descent of Man, he noted that tribes that demonstrated better team work usually triumph over those that do not.
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naturally occuring medicine dont usually have as wide and deep effect as artificial medicine. and knowledge of medicine is not genetically passed on (at least not for human)

lamarckism does not play any role in species survival, because it does not happen. it is not an "alternative" path of evolution, it is a mistaken path of evolution.

you have thick pads on your fingers and feet because your body has the ability to develop harder skins at places where more stress is applied. your fingers are more flexible because you practise it more and your muscle and tendons did not harden. these are naturally occuring adaptation that you as an individual can perform. at no time is this information passed on to your offsprings. a baby is always born is soft smooth soles even though their parents are hard laborers with calloused feet and hands.

AND, grass is not "medicine" to dogs, at least not in the sense you are implying.
dog eat grass


This post has been edited by lin00b: Jan 13 2010, 01:11 AM
lin00b
post Jan 13 2010, 07:45 PM

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QUOTE(Mesosmagnet @ Jan 13 2010, 03:25 PM)
.
It's true that through crossbreeding the chances of aa being expressed is significantly lowered, but only if we assume that the current population is comprised of more AA than Aa. If the opposite was true and there is more Aa than AA the chances of producing aa is increased rather than decreased. (Does this make sense? I'm a little bit confused)

Regarding your final statement. I totally agree that our current human population poses this instinct of protecting what we have. This is probably why natural selection doesnt work very well when human beings are concerned. While in the animal population, a weak lion cub which cannot cope with the harshness of the environment is regrettably left behind. Even though I want to accept the fact that it is natures way of functioning I cant help but to pity the ones left behind. And I think this is where we distinguish ourselves from the animal kind, even at the cost of evolution.
result of evolution is not to reduce bad genes, it is to reduce the expression of bad genes.

if bad genes are dominant - hence frequently expressed, that particular community will eventually be dead. if the bad genes are recessive, hence seldom expressed, the community will survive. if this surviving community resort to interbreeding, the odds of these bad genes being expressed is increased, and that is bad.

an interesting point is that majority of our genes are actually not expressed in any way. they may be junk, or extremely recessive

while you are referring to protecting the individual, i'm referring to protecting the species and community. the whole community suffer if the quality of the offspring produced is of frequently low quality. it is arguably better to allow only the better/fitter individual to reproduce and increasing the quality of the output. at least that's nature's way.
lin00b
post Jan 13 2010, 10:05 PM

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QUOTE(thesupertramp @ Jan 13 2010, 09:28 PM)
My point isn't about the differences between the effects of natural and modern medicine. The point is that humans have the unique ability to use tools. Modern medicine can be seen as one of humankind's greatest tools. Arguing medicine is counter productive to evolution would be similar (perhaps the same) as arguing the invention of guns have made the weak able to hunt for food, when in fact they should be left to die. Or the use of clothes have ensured the survival of those with less adipose tissues.

The use of tools is part of our evolutionary history and since we still exist, it can be said that it has served us well so far.

I was not referring to Lamarckism in its traditional sense. Genes cannot be altered, I know that. I was referring to the passing on of knowledge. We do not pass on knowledge of medicine genetically, but we do so in the form of books, lectures and teachings. In a sense, this is not Lamarckism, but it is close. We acquire that knowledge throughout life and pass it on. This ability to pass on knowledge is immensely significant in many species's survival.

Perhaps this is more akin to the Meme theory. If it is, then that further supports my point as modern medicine has grown and flourished.
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all those other "counter point" you use are actually true. although the exact line can be blurred. whatever artificial tools we make is not a result of our evolution. and by continuing to use them, we are in a sense limiting whatever natural selective pressure on use to be better biologically.

not to say tools are bad, but looking at a strictly evolution point of view, it is creating a weaker species biologically.

passing of knowledge is not lamarckism in any sense. say engineering parents, son may grow up to a profession that does not use engineering skills at all. whatever skill that the parents frequently use and depend upon is not transferred on to offspring

the passing of community-wide knowledge is good, but is fragile. knowledge is easily lost during catastrophes. after which the community has to start from a lower knowledge level, this is because those information is not guaranteed to pass on to future generation, unlike evolutionary genetic information.

 

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